Some of our current/ongoing research projects in the Korf lab include:
- Helping advance the state of the art in the field of genome assembly by organizing regular Assemblathons to evaluate genome assemblers
- Studying the evolution of centromere repeat sequences (with the Chan Lab)
- Investigating the elements that may be responsible for the process of Intron-Mediated Enhancement of gene expression, and analysing how this process might differ in different species (with Alan Rose)
- Building better HMMs that can predict alternative splicing
- Understanding genome-wide methylation patterns and the evolution of CpG islands (with the Chédin lab)
- Developing better models to explain transcription factor binding patterns (with the Segal Lab)
- Writing a book on Unix and Perl aimed specifically at biologists
Other interests (not actively being worked on, but things we may return to):
- Training gene finders to work with 'naked' genomes
- Genes inside genes - is there anything unusual about genes in the introns of other genes?
- Introns and splicing - how does splicing cope with very long and very short introns?
- Testing/evaluating motif finders
About Korf Lab
Korflab in the news
Jan 28, 2013:
A Haldane's Sieve Blog Post
by Keith Bradnam that discusses the Assemblathon 2 pre-print
Nov 12, 2012:
a feature on Danielle Lemay
by the Calfifornia Dairy Research Foundation
Mar 23, 2011:
A Nature news article
about genome assembly, with an interview of Ian Korf.
Our free 175-page primer that teaches the basics of Unix & Perl
Our book that greatly expands on our free primer.
Comprehensive online toolkit for sequence analysis and visualisation
Where we work
Part of the Genome Center