About Korf Lab

Research

Some of our current/ongoing research projects in the Korf lab include:

Helping advance the state of the art in the field of genome assembly by organizing regular Assemblathons to evaluate genome assemblers
Studying the evolution of centromere repeat sequences (with the Chan Lab)
Investigating the elements that may be responsible for the process of Intron-Mediated Enhancement of gene expression, and analysing how this process might differ in different species (with Alan Rose)
Building better HMMs that can predict alternative splicing
Understanding genome-wide methylation patterns and the evolution of CpG islands (with the Chédin lab)
Developing better models to explain transcription factor binding patterns (with the Segal Lab)
Writing a book on Unix and Perl aimed specifically at biologists

Other interests (not actively being worked on, but things we may return to):

Training gene finders to work with 'naked' genomes
Genes inside genes - is there anything unusual about genes in the introns of other genes?
Introns and splicing - how does splicing cope with very long and very short introns?
Testing/evaluating motif finders

About Korf Lab