Welcome to the latest version of the IMEter (v2.1). By assessing whether any individual sequence looks more like a promoter-proximal intron or a promoter-distal intron (for a given species of interest), the IMEter calculates if an intron is likely to enhance gene expression. Some introns that are closer to the transcription start site (TSS) are believed to contain signals that help increase gene expression. We therefore believe that higher IMEter scores likely indicate that an intron may enhance gene expression.
Reference: Parra, G., Bradnam, K., Rose, A. and Korf, I. Comparative and functional analysis of intron-mediated enhancement signals reveals conserved features among plants Nucleic Acids Research, 2011