My interests focus on using ChIP-seq and RNA-seq as tools to understand MeCP2's affect on transcription regulation in neuronal cells. I'm also interested in looking at copy number variations (CNV's) and how they relate to human neuronal diseases.
2010: Student Employee of the Year
2009: NIH Supplement Summer Research Grant for Students and Science Educators
DH Yasui, HA Scoles, SI Horike, M Meguro-Horike, KW Dunaway, DI Shroeder and JM LaSalle. (2011) 15q11.2 - 13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain. Hum Mol Genet 2011 Nov 15;20(22):4311-23.
R Artuso, FT Papa, E Grillo, M Mucciolo, DH Yasui, KW Dunaway, V Disciglio, MA Mencarelli, M Pollazon, M Zappella, G Hayek, F Mari, A Renieri, JM LaSalle, and F Ariani. (2011) Investigation of modifier genes with copy number variations in Rett syndrome. J Hum Genet. 2011 Jul;56(7):598-15. Doi: 10.1038/jhg.2011.50.
Singleton MK, Gonzales ML, Leung KN, Yasui DH, Schroeder DI, Dunaway K, LaSalle JM March 2011. MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. Neurobiol Dis. [Epub ahead of print]