About Korf Lab

Contact

dpmelters@ucdavis.edu

Daniël P. Melters

BMCDB Graduate Student

Research Interests

Daniël is a fourth year PhD student from the Biochemical, Molecular, Cellular and Developmental Biology (BMCDB) Graduate Group and he is a shared student with Simon Chan. Daniël is also a member of the Designated Emphasis in Biotechnology, and was a recipient of the NIH training grant in Biomolecular Technology.

Daniël joined the lab in Spring of 2009. His research project is focused on the evolution of the centromere tandem repeat sequences in hundreds eurkaryotes (plants, animals, fungi, protists and others) using bioinformatics. DNA sequences used to study these repeats come from different sequencing platforms, including Sanger, Illumina, 454, and PacBio.

Daniël received his BSc and MSc from Leiden University in the Netherlands. For his MSc he worked in Dr. Lipsky's lab at the NIH, studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in Prof. Dr. de Kloet's lab at the LACDR / Leiden University identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined Dr. Pearce's lab at UCSF, working on understanding the signaling cascade regulation that regulate sodium reabsorption in kidney epithelium cells upon aldosterone treatment.

Publications

  • Soundararajan R, Wang J, Melters DP, Pearce D. Glucocorticoid-induced leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization. J. Biol. Chem. 2010 Dec 17;285(51):39905-13. link
  • Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex.Proc. Natl. Acad. Sci. U.S.A. 2009 106(19):7804-7809. link
  • Soundararajan R, Wang J, Melters DP, Pearce D. Differential activities of glucocorticoid-induced leucine zipper protein isoforms. J. Biol. Chem.2007 Dec 14;282(50):36303-13. link

Links

Chasing the Red Queen

BMCDB Graduate Group Blog

About Korf Lab

Korflab in the news


Jan 28, 2013: A Haldane's Sieve Blog Post by Keith Bradnam that discusses the Assemblathon 2 pre-print


Nov 12, 2012: a feature on Danielle Lemay by the Calfifornia Dairy Research Foundation


Mar 23, 2011: A Nature news article about genome assembly, with an interview of Ian Korf.

Contact Us

For questions or comments about the website, please e-mail:

korflab AT ucdavis DOT edu

Contact information for specific members of our lab can be found on their personal pages.