shahrame@stanford.edu
Genetics Graduate Student
I completed my PhD on "Computational and Molecular Studies of Intron- Mediated Enhancement (IME) of Gene Expression in A. thaliana". IME refers to increase in gene expression via mRNA accumulation that is caused by inclusion of an intron close to the start of the transcription unit. IME is NOT a classical enhancer effect. To find out more about IME read:
Rose A.B., Emami S., Bradnam K., Korf I.F. (2011) Evidence for a DNA-based mechanism of intron-mediated enhancement, Frontiers in Plant Genetics and Genomics 2:98
Very broadly speaking, my current professional interests are in: synthetic biology, systems biology, complexity science, applications of machine learning algorithms in mining high-throughput "omics" data and entrepreneurship.
I am currently a postdoctoral fellow at Carnegie Institution for Science at Stanford. My current project is to use machine learning and synthetic biology techniques to characterize cis-regulatory elements in A. thaliana.
Jun 26, 2015: Keith Bradnam is interviewed by Frontline Genomics Magazine about his life in Bioinformatics.
Apr 8, 2015: Ian Korf is quoted in a Nature commentary article about Bioinformatics Service cores and the need for beter career paths for bioinformaticians.
Mar 16, 2015: Danielle Lemay is interviewed by the UC Davis News team about the new publication by herself, Kristen Beck (lead author), Ian Korf and others that describes new milk proteomes for human and macaque.
Apr 22, 2013: The Assemblathon 2 paper has won the 2013 BioMed Central Open Data award
Dec 10, 2013: A short piece in the UC Davis Alumni Magazine that discusses the new Genomics undergraduate major that Ian Korf co-developed.
Nov 26, 2013: Ian Korf writes a News & Views piece for Nature Methods about two new comparisons of programs that work with RNA-seq data
Nov 1, 2013: Keith B. and Kristen are both featured in a piece on Inquiring Minds as part of the new One UC Davis campaign.
Our free 175-page primer that teaches the basics of Unix & Perl
Our book that greatly expands on our free primer.
A regular discussion forum at the Genome Center for all things relating to sequence analysis
Where we work
Part of the Genome Center
For questions or comments about the website, please e-mail:
korflab AT ucdavis DOT edu
Contact information for specific members of our lab can be found on their personal pages.