About Korf Lab



Daniël P. Melters

Former BMCDB Graduate Student, now working for Shiv Grewal

Research Interests

Daniël was a PhD student from the Biochemical, Molecular, Cellular and Developmental Biology (BMCDB) Graduate Group and a shared student with Simon Chan. Danël was also a member of the Designated Emphasis in Biotechnology, and was a recipient of the NIH training grant in Biomolecular Technology.

Daniël joined the lab in Spring of 2009. His research project was focused on the evolution of the centromere tandem repeat sequences in hundreds eurkaryotes (plants, animals, fungi, protists and others) using bioinformatics. DNA sequences used to study these repeats come from different sequencing platforms, including Sanger, Illumina, 454, and PacBio.

Daniël received his BSc and MSc from Leiden University in the Netherlands. For his MSc he worked in Dr. Lipsky's lab at the NIH, studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in Prof. Dr. de Kloet's lab at the LACDR / Leiden University identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined Dr. Pearce's lab at UCSF, working on understanding the signaling cascade regulation that regulate sodium reabsorption in kidney epithelium cells upon aldosterone treatment.


  • PhD thesis, 2013
  • Melters, D.P., Bradnam, K.R., Young, H.A., Telis, N., May, R.M., Ruby, J.G., Sebra, R., Peluso, P., Eid, J., Rank, D., Garcia, J.F., DeRisi, J.L., Smith, T., Tobias, C., Ross-Ibarra, J., Korf, I.F., and Simon W.-L. Chan. Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution, Genome Biology, 2013, 14:R10
  • Melters, D.P., Paliulis L.V., Korf I., and Chan SW. Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis.. Chromosome Res., 2012, 7th July
  • Soundararajan R, Wang J, Melters DP, Pearce D. Glucocorticoid-induced leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization. J. Biol. Chem. 2010 Dec 17;285(51):39905-13. link
  • Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex.Proc. Natl. Acad. Sci. U.S.A. 2009 106(19):7804-7809. link
  • Soundararajan R, Wang J, Melters DP, Pearce D. Differential activities of glucocorticoid-induced leucine zipper protein isoforms. J. Biol. Chem.2007 Dec 14;282(50):36303-13. link


Daniël's blog

Chasing the Red Queen

BMCDB Graduate Group Blog

About Korf Lab

Korf Lab in the news

Jun 26, 2015: Keith Bradnam is interviewed by Frontline Genomics Magazine about his life in Bioinformatics.

Apr 8, 2015: Ian Korf is quoted in a Nature commentary article about Bioinformatics Service cores and the need for beter career paths for bioinformaticians.

Mar 16, 2015: Danielle Lemay is interviewed by the UC Davis News team about the new publication by herself, Kristen Beck (lead author), Ian Korf and others that describes new milk proteomes for human and macaque.

Apr 22, 2013: The Assemblathon 2 paper has won the 2013 BioMed Central Open Data award

Dec 10, 2013: A short piece in the UC Davis Alumni Magazine that discusses the new Genomics undergraduate major that Ian Korf co-developed.

Nov 26, 2013: Ian Korf writes a News & Views piece for Nature Methods about two new comparisons of programs that work with RNA-seq data

Nov 1, 2013: Keith B. and Kristen are both featured in a piece on Inquiring Minds as part of the new One UC Davis campaign.

More news

Contact Us

For questions or comments about the website, please e-mail:

korflab AT ucdavis DOT edu

Contact information for specific members of our lab can be found on their personal pages.